There is a huge weakness to Bisharp + Sylveon lead.. a +1 Bisharp basically OHKOs every pokemon except for Scrafty, which is also the reason for its Defiant boost, while Sylveon can OHKO Scrafty and deal about 50% of damage to every other pokemon with Hyper Voice.
Aegislash + M-Gardevoir/Sylveon is also scary, since Aegislash can take a Shadow Ball from M-Gengar and OHKO it back, it can escape from the Shadow Tag on last turn and it can deal a lot of damage to Gothitelle, Dewgong and Jigglypuff, while M-Garde/Sylveon finish the job spamming Hyper Voice.
Aegislash + M-Gardevoir/Sylveon is also scary, since Aegislash can take a Shadow Ball from M-Gengar and OHKO it back, it can escape from the Shadow Tag on last turn and it can deal a lot of damage to Gothitelle, Dewgong and Jigglypuff, while M-Garde/Sylveon finish the job spamming Hyper Voice.